Tag Archives: Antidepressants For Trauma

Antidepressants : Are Those Who Experienced Early Life Trauma Less Responsive To Them?

MDD, early life-trauma and antidepressants

Antidepressants And Childhood Trauma :

As part of the international Study to Predict Optimized Treatment for Depression (iSPOT-D) involving over one thousand individuals who had been diagnosed with major depressive disorder (MDD). research was undertaken to compare the prevalence of histories of early childhood trauma in this group with the same prevalence inĀ  a group of ‘healthy’ controls (this latter group was comprised of 336 matched individuals).

antidepressants and childhood trauma

Results :

Depressed individuals more likely to have suffered early-life stress (see below)

When the two groups were compared, it was found that :

  • In the group of individuals who had been diagnosed with major depressive disorder (MDD), 62.5% had suffered more than two traumatic events before the age of 18.
  • In the group of ‘healthy’ individuals, 28.4% had suffered more than two traumatic events before the age of 18.

(The

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